منابع مشابه
Hepatitis B Vaccines; Efficacy and Necessity of Booster Immunizations
Most hepatitis B (HB) vaccines are based on recombinant major S protein produced and purified from yeast. To decrease the number of vaccinations, several combination vaccines have been developed, and are commonly used for infant [1-3]. These include HB combined with diphtheria, tetanus, acellular pertussis, and inactivated poliovirus vaccine (DTaP–IPV–HB vaccine); combined hepatitis A and HB va...
متن کاملIs adolescent pertussis vaccination preferable to natural booster infections?
Pertussis is still poorly controlled in both adolescents and adults. As a result, an adolescent pertussis booster vaccine dose has already been implemented or decided on in many countries. The reasons for this have been twofold: a worrying increase of infections in the target group of adolescents and a wish to prevent serious pertussis disease among young yet unvaccinated, and partly vaccinated...
متن کاملImmunity to pertussis 5 years after booster immunization during adolescence.
BACKGROUND We conducted a 5-year follow-up study on the persistence of pertussis-specific antibody and cell-mediated immunity after booster immunization of adolescents aged 11-13 years with a tricomponent acellular pertussis vaccine (Boostrix; trials diphtheria-tetanus-acellular pertussis [Tdap]-004/030). METHODS Cellular and humoral immunity to pertussis toxin (PT), filamentous hemagglutinin...
متن کاملCost-effectiveness of pertussis booster vaccination in the Netherlands.
The aim of the current study is to estimate the epidemiological and economical consequences of several extended pertussis booster vaccination strategies and to explore the impact of parameters surrounded by large uncertainty on the cost-effectiveness. We developed an age structured transmission dynamic model to evaluate the impact of programs targeting (i) adolescents or adults using a single b...
متن کاملBordetella pertussis booster vaccination for health care personnel immediately following a pertussis outbreak in a hospital?
Pertussis, caused by the small gram-negative bacterium Bordetella pertussis, is a life-threatening disease in young infants. Although almost all mortalities occur in children aged !6 months, the bacterium causes significant morbidity in all age groups [1], and adolescents and adults are often the source of infection in small children. Symptoms may be the classic ones, with paroxysmal cough and ...
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ژورنال
عنوان ژورنال: Microbe Magazine
سال: 2012
ISSN: 1558-7452,1558-7460
DOI: 10.1128/microbe.7.153.1